"Our grants focus on basic and translational research in an effort to improve outcomes for children with brain tumors," says Dianne Traynor, Director of Research Funding and Advocacy at the Pediatric Brain Tumor Foundation. "We seek out research institutions with strong basic, translational and clinical brain tumor research programs as well as large pediatric brain tumor patient populations. The types of pediatric brain tumors being studied at PBTF Institutes range from highly malignant gliomas and medulloblastomas, to low grade tumors. Our goal is to develop strong collaborative research efforts between the PBTF Institutes that will fast forward discoveries for this patient population." Dr. Darell Bigner, director of the PBTF Institute at Duke, is working steadily toward that goal. "The PBTF Institute Program has been a major contributor to the advancement of the body of knowledge in the causation and treatment of pediatric brain tumors," Bigner says. "It has been invaluable as a mechanism for bringing together the most outstanding investigators in the field of pediatric neuro-oncology."The director of the PBTF Institute at the University of California San Francisco agrees. "The beauty, and thus the significance, of this award is that it encourages us to not only collaborate among ourselves to push the limits of discovery, but to work with other groups funded by the PBTF to enhance our research productivity," says Dr. Mitch Berger.